Serum Magnesium? RBC Magnesium?
What's the difference?
Thomas DeLauer breaks down the results of the Scottsdale Magnesium Study (SMS) that measured MagSRT™ in a placebo-controlled, human clinical trial of 91 participants on the latest #ScienceSaturday.
The study measured Serum Magnesium, Red Blood Cell (RBC) Magnesium, and Magnesium Deficiency symptoms. The results were published in the peer-reviewed Journal of the American College of Nutrition (JACN).
For more information about the study, or if you want to see the results yourself, click HERE.
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Transcript by Rev.com
- It's Thomas DeLauer with a science Saturday and I am pleased to announce, that we did a clinical trial.
- We published a clinical trial?
- [In Unison] We published a clinical trial?
- We published a clinical trial?
- Yeah, we published a clinical trial.
- That's right, the Journal of the American College of Nutrition, published a study, and we're on the forefront of it. Utilizing magnesium SRT from Jigsaw.
- So in this video I'm gonna give you the low down on most magnesiums that you'll find in the grocery store, and then I will give you the low down on this study and help you understand all the amazing things that we've found through this phenomenal Scottsdale magnesium study.
- So let's get straight to the facts. So, first of all magnesium can be a little bit sketchy, because a lot of times magnesium ends up not being absorbed very well. Now if you've ever taken magnesium sulfate, which is also known as epsom salt. You know that it actually makes you go to the bathroom quite fast. So it causes an osmotic effect within the colon, what that means is that it ends up changing up the skew of how water is in the colon versus out of the colon. Which can throw off mineral balances even more and cause you to have pretty loose stools and quite honestly very very uncomfortable.
- So when you look at a lot of magnesium products that are out there on the shelves in most stores, you're looking at things like magnesium oxide, magnesium carbonate, and the problem is these have a very low availability within the body. Which means they end up disturbing that overall osmotic balance we have in the colon and small intestine. So that bioavailability that is low, ends up causing all the GI discomfort that you would get with most magnesium.
- So what we did is we want to take a look at the different kinds of magnesium and how they're actually absorbed. So when you look at what physicians usually recommend for magnesium deficiency issues and things like that they usually recommend magnesium malate. Magnesium malate is a lot more expensive, but it does have a better bioavailability.
- So what we did with Jigsaw SRT, we took a look at something call dimagnesium malate. So malate just means that it's bound to malic acid, so when you look at dimagnesium malate what we did is we took two magnesium ions and bound them to malic acid. So we had a very bioavailable, very absorbable form of magnesium. Then we added an SRT component to make it sustain release so it took a longer period of time to absorb so you weren't just getting this massive influx that the body didn't know what to do with.
- So then, we get to the study, let's talk about what we did in Scottsdale here that was just published in 2018. So the study was published in the Journal of the American College of Nutrition in 2018, and it's called the Scottsdale Magnesium Study. We took a look at absorption, cellular uptake, but also magnesium deficiency symptoms to see if magnesium was truly absorbed and how it affected symptoms based on a questionnaire for participants that started.
- The study was done over a period of 30-90 days. We took 91 participants so there are 53 participants that took magnesium SRT from Jigsaw, okay, 500 milligrams. And then the rest took a placebo. So there were a few things they wanted to measure after they took the magnesium supplement. They wanted to measure of course their serum magnesium which is the overall levels of magnesium that ultimately ended up in their body.
- Then, they wanted to look at what's called RBC magnesium. RBC magnesium stands for red blood cell magnesium, this is very very important, what this is, this is the magnesium that is actually building up in your body and getting inside your bones. Getting with the red blood cells and marrow, getting into where it needs to go to have a long term effect on the body. So we wanted to look at that over a longer period of time. Serum magnesium can be looked at over a shorter period of time. That's more indicative of how well a product being absorbed, or how well is a mineral being absorbed in a shorter amount of time.
- So between four and eight hours after taking the magnesium is when they measured the overall serum magnesium, but after 30 and 90 is when they truly looked at the RBC to see how it was really building up in the body. So they found, there was a 22% increase in serum magnesium levels. Okay, this is pretty phenomenal, because before now, there wasn't any way to prove, whether a magnesium was absorbed or not. So when we have a 22% increase in serum magnesium that means we are literally getting 22% more magnesium in our body ready to be used.
- Now here's where it gets really fascinating. There was over a 30% increase in RBC magnesium over time. Again, the RBC magnesium is magnesium that's actually getting into the marrow and ultimately being used by the body. Competing against calcium, helping your body have a little bit more of a calming effect. Versus the exutory effect from excess calcium ions going through the body. So very very powerful that we saw that.
- Then at the beginning of the study, they did give all the participants a questionnaire. They wanted to note their magnesium deficiency symptoms. We're talking about things like leg cramps, we're talking about things like irritability, all these little things that go along with magnesium deficiency. Then at the end of 30 and 90 days they measured them again. They had them fill out another questionnaire to see how their overall symptoms were doing. Well guess what? After 90 days, 63% decrease in magnesium deficiency symptoms. That is powerful.
- So for someone that is normally having leg cramps or someone that is normally having the issues that arise from with magnesium deficiency, we were able to prove with the Scottsdale Magnesium Study that you can start to reduce magnesium deficiency symptoms. So if you combine that with accumulative buildup of magnesium in the body, you can start to get the results that you want. So hopefully this clears up a little bit about magnesium and how it truly works in the body.
- We're super proud to have published this study super proud to be a part of true science and actually changing lives. And I also want to add that 91% of the participants that participated in this study, tolerated the product very very well. Just so that you know, that is very very rare in a study you don't usually see something that well tolerated. Usually, it's like 70 or 80% stick through rate most people end up falling off. So not only do we find that it has amazing effects in the body, we also found that it's well tolerated amongst most people.
- One more thing to make this really really powerful, when you're normally looking at a clinical study usually you're looking at a one and a half times better placebo effect. Well in this case, five times better than placebo. So most pharmaceutical companies when they're doing any kind of clinical trial, all they're looking for is the drug to be one and a half times better than placebo. And that is kind of the gold standard. Well, MagSRT, five times better than placebo.
- So as always Jigsaw crew, you know I'm pleased to bring you this content. If you want to learn a little bit more about how this study worked, you can check it out by heading down to the link below. It'll give you all the details so you can see study the study for yourself and truly understand what we are doing to change the world. One person at a time. So remember, laughter is the best medicine, and magnesium is a close second. We'll see you soon.
For more information about the study, or if you want to see the results yourself, click HERE.